The Rise Of Early-Onset Colorectal Cancer (+How To Reduce Your Risk)

Colorectal cancer is expected to become the leading cancer death for young people1 (ages 20-49) in the U.S. by 2030, according to a Science review. Cases of early-onset colorectal cancer (EOCRC), aka young-onset colorectal cancer, have been rising 2% to 4% per year since the 90s in many countries, with more rapid increases occurring in patients under the age of 30.

Colorectal cancer is one of the most common forms of cancer in the U.S. and the second leading cause of cancer death (after lung cancer), accounting for 9% of all cancer mortalities in 2020, per the CDC. 

In addition to rising risk factors, evidence shows that failing to get enough of certain nutrients (like vitamin D) can increase the risk of developing colorectal cancer.

According to a 2019 Journal of the National Cancer Institute study, vitamin D deficiency (which affects 29% of U.S. adults2) increases risk of colorectal cancer by 31%3. Higher circulating vitamin D levels [i.e., 25(OH)D] were found to lower CRC risk in women substantially compared to men.

To maintain optimal vitamin D levels (again, 50 ng/ml) science shows you need a daily intake of 5,000 IU of vitamin D3 (not D2). Unfortunately, it's nearly impossible for most people to get there via food and sunshine alone.

Early-onset colorectal cancer is rising at a rapid rate—especially for Americans under the age of 30. Research also shows that vitamin D deficiency increases colorectal cancer risk by 31%.